ea0044p123 | Neoplasia, cancer and late effects | SFEBES2016
Lines Kate E
, Stokes Victoria
, Grozinsky-Glassberg Simona
, Yates Christopher J
, Thakker Rajesh V
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by the combined occurrence of parathyroid tumours, and neuroendocrine tumours (NETs) of the pancreas and pituitary. Reliable biomarkers, ideally in plasma or serum, for the early detection and recurrence of MEN-1 associated tumours, and especially pancreatic NETs are required, and we explored the potential use of microRNAS (miRNAs), which are small non-coding RNAs that bind target mRNAs ...